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According to ICH Q6B guidelines, impurities in biological products can be classified as process-related or product-related. Process-related impurities include those that are derived from the manufacturing process (e.g., cell substrates, cell culture media components or downstream processing). Product-related impurities in the drug substance are molecular variants with properties different from those of the desired product formed during manufacture or storage. To characterize these impurities, we conducted six (6) unique analytical techniques for the isolation and characterization of process- and product-related impurities.
Muira Puama – Is derived from the bark of a tree or its roots. This small tree is native to the Amazonian region of South America and has a plethora of uses among the indigenous peoples of the Amazon, including the following: adaptogen, alopecia (applied topically for hair loss), anorexia, antinociceptive, antioxidant, aphrodisiac, ataxia, beri beri (vitamin deficiency disease), debility, digestive problems, dysentery, fatigue, impotence, neurasthenia, nerve tonic, rheumatism, stimulant, tonic (adding bark decoction to a bath), paralysis, and tremors (Quattrocchi, 2012; Piato et al., 2010; Berdonces, 2009; Duke et al., 2009; Taylor, 2005; Rutter, 1990). Muira puama is an important ingredient of “catuama”, a medicinal poly-herbal combination used in South America, also composed of guaraná (Paullinia cupana), ginger (Zingiber officinale), and Trichilia catigua (Quattrocchi, 2012). One of the main active ingredients in muira puama is an alkaloid known as muirapuamine (Lorenzi and Matos, 2008).
Saffron is a delicious spice that comes from the Crocus sativus flower. Its many traditional uses range from reducing stress to acting as an aphrodisiac, especially for people on antidepressant medications. Some studies show that saffron could improve sexual dysfunction caused by antidepressants (26Trusted Source). What’s more, one review of six studies reported that saffron improved erectile function, sexual desire, and satisfaction in men. However, there were significant flaws in the methods of the analyzed studies, which weakens these findings. Additionally, a review of 5 studies in 173 people noted that saffron significantly improved various aspects of sexual pleasure, desire, and arousal, but the results among the studies varied significantly. The effects of saffron on improving sexual function in people who don’t have depression or are not taking antidepressants are mixed.
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Treatments to increase libido: Estrogen creams: these can help you when your estrogen level is low, and your vagina no longer lubricates causing pain during intercourse. Pills for erectile dysfunction: Occasionally, doctors prescribe such drugs to women when they fail to excite or reach orgasm. Pills are meant to increase blood flow to the genital area. Testosterone: This hormone plays an important role in a woman’s sexual function but decreases with age. It is usually prescribed for women who have a low libido due to menopause, or for those whose ovaries have been removed.
A lot of mainstream media focuses on the differences between men’s brains and women’s brains, including when it comes to sex. But brain-wise, men and women actually aren’t that different. One 2012 study involved viewing the brain through an fMRI machine while subjects watched erotic videos. The fMRI machine helped the researchers see how the brain was affected during arousal. It found that, while sexual stimuli activated the amygdalas and thalami more in men, it generally had a similar effect on all subjects. It’s worth noting that these studies often don’t include intersex and transgender participants. Discover more info on supercoreintl.com.
Vitamins to support erection in 2024: Evaluation of Erectile Dysfunction: It is important to understand that both organic and psychosocial factors play a role in the etiology of erectile dysfunction. Hence a thorough detailed history without too many prying questions is key. Sometimes patients may feel embarrassed to answer direct questions and hence a self administered questionnaire may help. Sometimes picture cards explaining the anatomy of erection may also be used for explaining.
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Potential anti-tumour effects: Preliminary studies propose that cordyceps may offer protection against cancer and inhibit the growth of certain types of cancer cells including lung, colon, skin and liver cancers. According to a study published in Journal of Microbiology and Biotechnology in 2008, a cordyceps extract was able to trigger apoptosis (cell death) in breast cancer cells in test tube studies. Similar results have been seen with colon cancer cells. The cordycepins in the cordyceps appear to be toxic to leukemia cells. Studies in mice have also shown that cordyceps have anti-tumour effects on lymphoma, melanoma and lung cancer.